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近年来,国内外不少学者已对乙型肝炎病毒（HBV）感染与原发性肝癌（PHC）的血清学标志物组合关系进行了不少研究。现将我院近两年来对38例PHC患者的5项乙肝血清标志物检出结果报道如下:1 资料与方法1.1 一般资料 本组38例PHC患者系我院1997—1998年住院病人,年龄:24～78岁,平均55岁。性别:男30例,女8例。均经B超探查发现有肝脏占位性病变;甲胎蛋白水平均高于0.4 mg/L。除本组38例PHC患者外,另选择肝硬变患者20例,按内科学诊断标准确诊。对照组30例,为本院血库健康献血员。1.2 方法 乙肝血清学标志物（HBsAg、HBS,HBeAg,抗-HBe,抗-HBc）测定与甲胎蛋白均采用ELISA法。试剂为上海科华生产的乙肝试剂盒与郑州博赛公司生产的甲胎蛋白试剂盒。B型超声诊断机为日本产阿洛卡630型。
In recent years, many scholars at home and abroad have conducted a lot of research on the relationship between serological markers of hepatitis B virus (HBV) infection and primary liver cancer (PHC). The results of five hepatitis B serum markers detected in 38 patients with PHC in our hospital in the past two years are reported as follows: 1 Materials and Methods 1.1 General Information 38 patients with PHC in this group were hospitalized in our hospital from 1997 to 1998. Age: 24 to 78 years old, an average of 55 years old. Gender: 30 males and 8 females. All patients were found to have hepatic space-occupying lesions by B-scan exploration; the level of AFP was higher than 0.4 mg/L. In addition to 38 patients with PHC in this group, 20 patients with cirrhosis were selected and diagnosed according to internal diagnostic criteria. In the control group, 30 patients were blood donor healthy blood donors. 1.2 Methods Hepatitis B serological markers (HBsAg, HBS, HBeAg, anti-HBe, anti-HBc) and alpha-fetoprotein were detected by ELISA. The reagents were Hepatitis B kits produced by Shanghai Kehua and AFP kits produced by Zhengzhou Bossa. The B-type ultrasonic diagnostic machine is the Japanese Alocar 630 type.