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目的提高临床医师对多原发大肠癌的重视程度，研究腺瘤与肠癌的关系。方法总结８４３例大肠癌中多原发癌２２例（同时癌１７例，异时癌５例）的临床资料。结果多原发癌检出率２．６１％；２２例共有癌灶４９个，乙状结肠以下占６２．６％；２２例中共检出腺瘤３１个，癌变息肉达６１．２％，亦多分布在乙状结肠和直肠。结论多原发大肠癌并不少见，多原发大肠癌与腺瘤之间关系密切。对大肠癌患者行肠镜检查时，对所见息肉均应常规活检，并治疗，以减少多原发大肠癌的发生。
Objective To improve clinicians’ emphasis on multi-primary colorectal cancer and study the relationship between adenoma and colorectal cancer. Methods The clinical data of 843 cases of multi-primary cancer in 22 colorectal cancers (17 simultaneous cancers and 5 heterogeneous cancers) were summarized. Results The detection rate of multiple primary cancers was 2.61%. There were 49 lesions in 22 cases and 62.6% in the sigmoid colon. Twenty-one adenomas were detected in 22 cases and 61.2% of cancerous polyps were found. In the sigmoid colon and rectum. Conclusions Multiple primary colorectal cancers are not uncommon. Multiple primary colorectal cancers are closely related to adenomas. When enteroscopy is performed on patients with colorectal cancer, they should undergo routine biopsy and treatment in order to reduce the occurrence of multiple primary colorectal cancers.