菌阳肺结核的短程化疗是严格的抗菌疗法。国内外多使用3药9个月或4药6个月固定化疗期。但我们认为,化疗开始时的细菌学变化极不相同,大多数病例在化疗2个月时痰菌阴转,并持续阴性直到停药。对此类病例再化疗6个月或9个月显然意义不大。基于此,我院自1987～1991年应用2HRZS/4HR 6个月方案和2HRS/HR不固定化疗期方案治疗54例初治菌阳肺结核,并 Bacterial lung tuberculosis short-course chemotherapy is a strict antibacterial therapy. At home and abroad to use more than 3 drugs 9 months or 4 drugs 6 months fixed chemotherapy. However, in our opinion, the bacteriological changes at the start of chemotherapy are very different. In most cases, the sputum is turned negative at 2 months of chemotherapy and remains negative until discontinuation. Re-chemotherapy in such cases 6 months or 9 months obviously not significant. Based on this, our hospital from 1987 to 1991 application of 2HRZS / 4HR 6 months regimen and 2HRS / HR chemotherapy regimen during the treatment of 54 untreated bacteria positive pulmonary tuberculosis, and