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目的:观察心理干预在非小细胞肺癌患者首次化疗中的应用效果。方法:随机抽取2009年5月至2013年5月期间我院收治的非小细胞肺癌确诊患者94例,PS评分均为0分~1分,1:1随机分为干预组与对照组,所有患者化疗方案均为吉西他滨+顺铂,干预组患者增加心理干预,分别在治疗前和治疗后对患者进行SAS以及SDS评分,并在治疗后对患者生活质量进行评分。结果:治疗前两组患者的平均SAS及SDS评分差异无统计学(P>0.05),干预组患者治疗后的平均SAS评分为(22.19±7.84),明显低于治疗前(42.06±10.74),差异有统计学意义(t=22.511,P<0.05),对照组的平均SAS评分为(41.76±9.58),与治疗前(45.59±14.62)相比差异无统计学,两组比较干预组的平均SAS评分明显低于对照组(t=11.946,P<0.05);干预组治疗后的平均SDS评分为(25.49±6.12),明显低于治疗前(46.15±13.84),差异有统计学意义(t=26.490,P<0.05);对照组的平均SDS评分为(43.72±14.67),与治疗前相比无统计学差异,组间比较干预组的平均SDS评分明显低于对照组(t=20.818,P<0.05)。干预组患者首次化疗结束后进行生活质量评分得分为4-5分的明显高于对照组(χ~2=29.716,P<0.05),差异具有统计学意义。结论:在非小细胞肺癌患者首次进行化疗的过程中进行心理干预可有效提高其治疗后的生活质量,值得临床推广。
Objective: To observe the effect of psychological intervention in the first chemotherapy of patients with non-small cell lung cancer. Methods: Ninety-four patients with NSCLC who were admitted to our hospital from May 2009 to May 2013 were randomly selected. The PS scores ranged from 0 to 1 and were randomly divided into intervention group and control group Patients in the chemotherapy regimen were gemcitabine plus cisplatin. Patients in the intervention group were given psychological interventions. SAS and SDS scores were obtained before and after treatment, and the quality of life of patients was scored after treatment. Results: The mean SAS and SDS scores of the two groups before treatment were not statistically different (P> 0.05). The average SAS score of the intervention group was (22.19 ± 7.84), which was significantly lower than that before treatment (42.06 ± 10.74) The difference was statistically significant (t = 22.511, P <0.05), the average SAS score of the control group was (41.76 ± 9.58), compared with the pre-treatment (45.59 ± 14.62), there was no statistical difference between the two groups SAS score was significantly lower than the control group (t = 11.946, P <0.05); the mean SDS score of the intervention group after treatment was (25.49 ± 6.12), significantly lower than that before treatment (46.15 ± 13.84), the difference was statistically significant = 26.490, P <0.05). The average SDS score of the control group was (43.72 ± 14.67), which was not significantly different from that before treatment. The average SDS score of the intervention group was significantly lower than that of the control group (t = 20.818, P <0.05). The quality of life score of 4-5 points was significantly higher in the intervention group than that in the control group after the first chemotherapy (χ ~ 2 = 29.716, P <0.05), and the difference was statistically significant. Conclusion: Psychological intervention during the first chemotherapy in patients with non-small cell lung cancer can effectively improve the quality of life after treatment, which is worthy of clinical promotion.