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目的探讨儿童下呼吸道阴沟肠杆菌感染的临床特点。方法回顾分析54例不同年龄儿童下呼吸道阴沟肠杆菌感染的临床症状、体征、实验室检查等。结果 54例中,发热12例(22.2%),咳嗽36例(66.7%),气促22例(40.7%),肺部闻及湿啰音32例(59.3%),肺部闻及干啰音11例(20.4%),WBC>10×109/L 23例(42.6%),肝功能异常36例(66.7%),肌酸激酶同功酶升高7例(13.0%),C-反应蛋白(CRP)升高2例(3.7%),血清IgA下降17例(31.5%),血清IgG下降11例(20.4%)。54例患儿痰培养阴沟肠杆菌均阳性,阴沟肠杆菌超广谱β-内酰胺酶阳性3例(5.6%)。结论下呼吸道阴沟肠杆菌感染临床症状以咳嗽和气促为主,WBC和CRP升高不明显,预后较好。
Objective To investigate the clinical features of Enterobacter cloacae infection in children with lower respiratory tract. Methods Retrospective analysis of 54 cases of children with different ages of lower respiratory tract enterobacter cloacae infection clinical symptoms, signs, laboratory tests. Results In 54 cases, 12 cases (22.2%) were fever, 36 cases (66.7%) cough, 22 cases (40.7%) were shortness of breath, 32 cases (59.3%) of lung were smear and wet, and the lungs were well and dry Eleven patients (20.4%) had hearing loss, 23 patients (42.6%) had WBC> 10 × 109 / L, 36 patients (66.7%) had abnormal liver function and 7 patients (13.0%) had elevated creatine kinase isoenzymes Elevated protein (CRP) in 2 cases (3.7%), serum IgA decreased in 17 cases (31.5%), serum IgG decreased in 11 cases (20.4%). 54 cases of sputum culture of Enterobacter cloacae were positive, Enterobacter cloacae extended-spectrum β-lactamase-positive in 3 cases (5.6%). Conclusions The clinical symptoms of Enterobacter cloacae infection in lower respiratory tract are mainly cough and shortness of breath. The WBC and CRP are not obviously increased and the prognosis is good.