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目的评价尼莫地平联合硫酸镁治疗上尿路结石的疗效。方法将62例上尿路结石患者随机分为两组,治疗组32例,对照组30例,对照组常规应用控制感染、多饮水、输液及止痛治疗,治疗组在此基础上加用尼莫地平片20mg,3次/d,口服,并应用0.9%氯化钠溶液250ml加25%硫酸镁5ml静脉滴注,1次/d,疗程7d。结果治疗组在疗程内结石顺利排出的时间短于对照组(P<0.05),需转外科手术者治疗组4例,对照组6例,两组比较差异无统计学意义(P>0.05)。结论尼莫地平联合硫酸镁治疗有利于上尿路结石排出,值得进一步尝试。
Objective To evaluate the efficacy of nimodipine combined with magnesium sulfate in the treatment of upper urinary tract calculi. Methods Sixty-two cases of upper urinary tract calculi were randomly divided into two groups: treatment group (32 cases) and control group (30 cases). In the control group, the patients were given routine infection control, drinking water, infusion and analgesic treatment. Tablets 20mg, 3 times / d, orally, and the application of 0.9% sodium chloride solution 250ml plus 25% magnesium sulfate 5ml intravenous infusion, 1 / d, treatment 7d. Results In the treatment group, the time for the smooth discharge of stones was shorter in the treatment group than in the control group (P <0.05). In the treatment group, 4 cases needed surgery and 6 cases in the control group. There was no significant difference between the two groups (P> 0.05). Conclusion Nimodipine and magnesium sulfate treatment is conducive to the discharge of upper urinary tract stones, it is worth further attempts.