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许多年来认为放疗对于软组织肉瘤的治疗无效。安德森医院的Suit等从1960年便开始认为局部手术切除加放疗能有效地达到肿瘤长期局部控制,目前普遍认为这种方法很有效,在某些情况下其局部控制情况甚至比截肢术更好。虽然这一观点已被广泛接受,但对于既达到最好的局部控制,又尽可能降低正常组织损伤所采取的具体技术仍然不一致。为尽可能提高治疗比。目前正在对各种治疗方法进行研究,包括术前放疗、术后放疗、组织间插植疗法、术前放疗+化疗、高LET射线照射等。改良的放疗技术已得到愈来愈广泛的接受,并被用于治疗既往认为属于放射抵抗性肿瘤。
For many years radiotherapy has been considered ineffective for the treatment of soft tissue sarcomas. In 1960, the Anderson Hospital’s Suit et al. began to believe that local surgery and radiotherapy can effectively achieve long-term local control of tumors. Currently, this method is generally considered to be effective. In some cases, local control is even better than amputation. Although this view has been widely accepted, the specific techniques used to achieve the best local control while minimizing damage to normal tissue remain inconsistent. To increase the treatment ratio as much as possible. Research is currently being conducted on a variety of treatment methods, including preoperative radiotherapy, postoperative radiotherapy, tissue implantation therapy, preoperative radiotherapy + chemotherapy, high LET radiation and so on. Improved radiotherapy techniques have become more widely accepted and used to treat previously considered radioresistant tumors.