硫杂脯氨酸是一种能使癌细胞逆转为正常细胞的新型抗癌药物,它的一系列衍生物具有多种抗癌疗效,而2-取代衍生物具有令人感兴趣的抗癌作用。本文在合成一系列(10种)2-芳基硫杂脯氨酸衍生物基础上,测定了合成反应动力学的有关参数,初步探讨合成反应机理。 Thymol is a novel anticancer drug that reverses cancer cells into normal cells. A series of its derivatives have a variety of anti-cancer effects, while 2-substituted derivatives have an interesting anti-cancer effect . In this paper, based on the synthesis of a series of (10) 2-aryl thioproline derivatives, the parameters of the reaction kinetics were determined, and the mechanism of the synthesis reaction was preliminarily discussed.