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本文通过对52例心功能不全患者血浆心钠素水平的观察,发现心功能不全患者血浆心钠素(1212.6±186.9pg/ml)明显高于对照组(454.4±72.5pg/ml,P<0.01);由于病情轻重不同,病程长短不同,心钠素水平也各不相同;经治疗病情改善后,心钠素水平也趋于下降,接近正常对照值(从944.5±186.4pg/ml下降到398.2±74.8pg/ml,P<0.01).结果表明,心功能不全时血浆心纳素浓度增加有利于心功能的纠正,是机体重要的保护性代偿机制.
In this paper, 52 cases of cardiac dysfunction in patients with plasma atrial natriuretic peptide levels observed in patients with cardiac dysfunction, plasma atrial natriuretic peptide (1212.6 ± 186.9pg / ml) was significantly higher than the control group (454.4 ± 72.5pg / Ml, P <0.01); atrial natriuretic peptide levels also varied due to different disease severity and duration of disease; atrial natriuretic peptide also tended to decrease after treatment, approaching the normal control value (from 944 .5 ± 186.4 pg / ml to 398.2 ± 74.8 pg / ml, P <0.01). The results show that cardiac insufficiency increases plasma concentrations of plasma concentrations of cardiac function is conducive to correct, the body is an important protective compensation mechanism.