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目的 :探讨液体复苏联合抗感染的综合疗法治疗感染性休克的临床疗效。方法 :选取280例感染性休克患者为研究对象,根据其意愿分成液体复苏组(A组,n=140)和对照组(B组,n=140)两组,观察并记录两组患者用药后治疗目标达到时间、治疗第1h输液量、ICU总住院时间等指标差异,对比其治疗后死亡及肺水肿发生情况。结果 :1 A组患者在治疗达标时间及ICU总治疗时间对比上均明显短于B组,对比差异明显;B组治疗第一小时输液量明显低于A组;2 A组死亡率为15.0%,明显低于B组的42.8%,对比差异具有统计学意义;两组在治疗肺水肿发生率对比上无明显差异。结论 :对感染性休克患者予以液体复苏联合抗感染治疗方案,临床效果确切,预后质量良好,值得临床推广。
Objective: To investigate the clinical efficacy of liquid resuscitation combined with anti-infective therapy in the treatment of septic shock. Methods: Two hundred and seventy patients with septic shock were selected and divided into liquid resuscitation group (group A, n = 140) and control group (group B, n = 140) according to their willingness. Two groups of patients were observed and recorded after treatment The treatment goal to reach the time, the first hour of treatment infusion, ICU total length of stay and other indicators of differences compared to its death and pulmonary edema after treatment. Results: In group A, the time of reaching the standard of treatment and the total treatment time of ICU were significantly shorter than that of group B, the difference was obvious; the infusion volume of group A in the first hour was significantly lower than that in group A; the mortality in group A was 15.0% , Significantly lower than 42.8% in group B, the difference was statistically significant; the two groups in the treatment of pulmonary edema incidence of no significant difference. Conclusion: The treatment of septic shock patients with liquid resuscitation combined anti-infective treatment program, the exact clinical effect, the prognosis of good quality, worthy of clinical promotion.