卓艾氏综合征(ZES)的诊断明确,但40％具有隐性肿瘤,常持续用药物治疗或姑息性手术治疗。由于手术失败,术前肿瘤定位具有日益重要的作用。CT对确定肝转移敏感,可作为筛选检查。如属阳性,做选择性内脏动脉造影,后者可确诊原发性胰腺肿瘤或肝脏小转移灶,但不能检出直径小于1.5cm肿瘤。1979年作者开始采用经肝、胰和肝静脉取血样(THVS)测量病人的胃泌素水平,已证实对隐性肿瘤定位有效,经上述检查后,可预期术中找到肿瘤。作者应用THVS检查46例,除1例外均发现胃泌素瘤,该例拟定手术前夕发生十二指肠巨大溃疡穿孔。 The diagnosis of Zou’er Syndrome (ZES) is clear, but 40% have a recessive tumor and are often treated with medication or palliative surgery. Due to the failure of surgery, preoperative tumor localization has an increasingly important role. CT is sensitive to liver metastasis and can be used as a screening test. If it is positive, selective visceral artery angiography is performed. The latter can diagnose primary pancreatic tumors or small liver metastases, but tumors smaller than 1.5 cm in diameter cannot be detected. In 1979, the authors began to use the liver, pancreas, and hepatic vein blood samples (THVS) to measure gastrin levels in patients. It has been proved effective in locating recessive tumors. After the above examinations, tumors can be expected to be found during surgery. The authors used the THVS to examine 46 cases. Gastrin tumors were found except for one exception. In this case, a large duodenal ulcer perforation was planned.