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Objective:To evaluate the safety & efficacy ofMaa-Lact granules for its galactogougue activity inHoltzman rats and its effect on suckling pups.Methods:GroupI rats were treated as control, groupII andIII rats were treated with500 mg/kg,1000 mg/kg ofMaa-Lact granules for21 days. Weekly body weights of dams and pups were collected, litter survivability for22 days and ocular blood samples were collected on1st day of parturition and21st day of post parturition for the estimation of prolactin levels.On21st day blood samples were collected from retro-orbital sinus for haemotological and biochemical estimations.On the same day of weaning rats were sacrificed and subjected to necropsy and individual organ weights were recorded.Results:No significant difference in weekly food weight consumption, body weights between control & treated groups with normal clinical signs.There is no mortaly in dams throught the study period with no significant difference in pups weights.The percentage mortality in pups was14.43%,14.07%, and 13.42% in groupI, groupII and groupIII, respectively.The histopathological finding has shown that treated groups have less convulution and adipose tissue depositionalong with increase in length and branching of lactiferous duct and alveolar size.Conclusion:Based on above results, it can be concluded thatMaa-Lact posseses significant galctogogue activity.