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为探索进一步控制和降低两种按蚊共存地区间日疟发病率的措施，选择六合县马鞍乡为纵向观察试点，采取灭蚊与传染源查治措施的不同组合，观察１９９１～１９９６年的年发病率、发热病人血检阳性率、小学生疟原虫阳性率、间接荧光抗体（ＩＦＡ）阳性率、按蚊种群比例和密度等指标的变化情况。结果在采取灭蚊措施时，年发病率出现明显下降；当无灭蚊措施时，则发病率回升。发热病人血检阳性率、ＩＦＡ阳性率和年发病率的变化基本吻合。结果表明：两种按蚊共存地区，采取灭蚊措施能有效地控制间日疟发病率，除年发病率外，发热病人血检疟原虫阳性率和ＩＦＡ阳性率也可用于评价不同防治措施的效果。
In order to explore measures to further control and reduce the incidence of vivax malaria in the areas where two species of Anopheles coexist, we selected Ma’an Township in Liuhe County as a longitudinal observation pilot and adopted different combinations of anti-mosquito and source-based investigation and treatment measures to observe the year 1991-1996 Incidence, the positive rate of blood test in fever patients, the positive rate of Plasmodium of primary school students, the positive rate of indirect fluorescent antibody (IFA), the proportion and density of Anopheles population. Results In the anti-mosquito measures taken, the annual incidence showed a significant decline; when there is no anti-mosquito measures, then the incidence rose. Fever patients blood test positive rate, IFA positive rate and annual change in the basic agreement. The results showed that mosquito control could effectively control the incidence of P.vivax in the coexisting areas of Anopheles mosquitoes, except for the annual incidence, the positive rates of Plasmodium falciparum and IFA in the febrile patients could also be used to evaluate the effects of different control measures effect.