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本文报道用原子吸收法对20例胃癌和20例萎缩性胃炎患者血清、头发、胃粘膜活检组织中锌、铜和铁含量的测定结果,并与对照组进行比较。结果:与萎缩性胃炎组和对照组相比,胃癌组血清锌降低,而血清铜和血清铜/锌比值升高。胃癌组和萎缩性胃炎组血清铁和头发锌均低于对照组。胃粘膜活检组织中锌、铜、铁含量差别无统计学意义。对胃癌、萎缩性胃炎与锌、铜、铁含量变化的因果关系和临床意义进行了讨论。
This paper reports the results of determination of zinc, copper, and iron in serum, hair, and gastric mucosa biopsy in 20 patients with gastric cancer and 20 patients with atrophic gastritis by atomic absorption spectrometry, and compared with the control group. RESULTS: Compared with the atrophic gastritis group and the control group, serum zinc decreased in the gastric cancer group, and serum copper and serum copper/zinc ratio increased. Gastric iron and hair zinc were lower in the gastric cancer group and atrophic gastritis group than in the control group. There was no significant difference in the contents of zinc, copper, and iron in the biopsy tissues of gastric mucosa. The causality and clinical significance of changes in gastric cancer, atrophic gastritis, zinc, copper, and iron levels were discussed.