1 材料1.1 动物 Wistar大白鼠,体重90g～110g,雌雄各半,由预防医学科学院实验动物中心提供。1.2 药物 舒肝乐(SGL)冲剂,批号:940814,由吉林省中医中药研究院提供。2 方法 取健康大鼠,饲喂观察1周,选60只随机等分3组,每组雌雄各10只。2、3组给药,剂量分别为30g/kg和3g/kg(相当于临床用量的60倍和6倍)。1组为对照组,给等体积蒸馏水。以上各组每日灌胃1次,连续2个月。 1 Materials 1.1 Animals Wistar rats weighing 90 g to 110 g, half male and half male, were provided by the Experimental Animal Center of the Academy of Preventive Medicine. 1.2 Drugs SGL granules, lot number: 940814, provided by Jilin Provincial Institute of Traditional Chinese Medicine. 2 Methods Healthy rats were observed for 1 week after feeding and 60 were randomly divided into 3 groups with 10 males and 10 females in each group. Group 2 and 3 were administered at doses of 30 g/kg and 3 g/kg (equivalent to 60 and 6 times the clinical dose). One group was a control group and an equal volume of distilled water was given. The above groups were fed once a day for 2 consecutive months.