通过所搜集的10例临床病例复习脆性糖尿病的诊断、治疗。结论:心理问题及胰岛素治疗的中断是血糖波动特别是酮症的首要原因,代谢异常是第二位的因素,对患者进行心理治疗,寻找并纠正可能因素。同时正规胰岛素治疗,能达到满意疗效。 Through the collection of 10 cases of clinical diagnosis of brittle diabetes diagnosis and treatment. Conclusions: Psychological problems and interruption of insulin therapy are the primary causes of blood glucose fluctuations, especially ketosis. Metabolic abnormalities are the second most important factor. Patients are psychologically treated to find and correct possible causes. At the same time regular insulin therapy, can achieve satisfactory results.