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目的探讨正电子发射计算机体层摄影(PET)-CT在肺部病变中的临床应用价值。方法回顾性分析49例因肺部病变行PET-CT检查的图像资料,将全部病例按照肺内原发病变、转移性淋巴结病变、远处转移性病变进行编组,以其病理或长期随访结果为标准,与CT比较,评价PET-CT的临床应用价值。统计学分析采用χ2检验。结果肺内原发病灶共50处,PET-CT和CT的诊断准确率、敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)分别为90·0%、95·2%、62·5%、93·0%、71·4%和74·0%、76·2%、62·5%、91·4%、33·3%,PET-CT的诊断准确率与CT比较,差异有统计学意义(P<0·05);转移性淋巴结病变,PET-CT和CT的诊断准确率、敏感性、特异性、PPV、NPV分别为97·9%、100·0%、96·4%、95·5%、100·0%和69·3%、61·9%、75·0%、65·0%、72·4%,PET-CT的诊断准确率显著高于CT(P<0·01);远处转移性病变,PET-CT和CT的诊断准确率、敏感性、特异性、PPV、NPV分别为95·0%、91·6%、100·0%、100·0%、93·2%和87·8%、68·7%、100·0%、100·0%、82·8%,PET-CT和CT的诊断准确率比较,差异无统计学意义(P>0·05)。结论PET-CT在肺部病变的定性诊断及肺癌的临床分期方面具有重要的临床应用价值。
Objective To investigate the clinical value of positron emission computed tomography (CT) -CT in lung diseases. Methods A retrospective analysis of 49 cases of lung disease due to PET-CT examination of the image data, all cases in accordance with the primary lung lesions, metastatic lymph node disease, distant metastatic disease grouping, with its pathological or long-term follow-up results were Standard, and CT, evaluate the clinical value of PET-CT. Statistical analysis using χ2 test. Results There were 50 primary lesions in the lung. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of PET-CT and CT were 90.0% and 95.2% , 62.5%, 93.0%, 71.4% and 74.0%, 76.2%, 62.5%, 91.4% and 33.3% respectively. The diagnostic accuracy of PET-CT and CT (P <0.05). The diagnostic accuracy, sensitivity, specificity, PPV and NPV of metastatic lymph node lesions, PET-CT and CT were 97.9% and 100.0% respectively, and the differences were statistically significant , 96.4%, 95.5%, 100.0% and 69.3%, 61.9%, 75.0%, 65.0% and 72.4% respectively. The diagnostic accuracy of PET-CT was significantly higher The diagnostic accuracy, sensitivity, specificity, PPV and NPV of distant metastatic disease, PET-CT and CT were 95.0%, 91.6% and 100.0 respectively in CT (P <0.01) %, 100.0%, 93.2% and 87.8%, 68.7%, 100.0%, 100.0% and 82.8% respectively. There was no significant difference in the diagnostic accuracy between PET-CT and CT Statistical significance (P> 0.05). Conclusion PET-CT has important clinical value in the diagnosis of lung lesions and the clinical staging of lung cancer.