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目的探讨药物联合治疗内分泌功能障碍导致卵泡发育不全的不孕疗效,总结医学经验,从而为临床提供借鉴意义。方法选取本院2011年收治内分泌功能障碍不孕患者85例,采用克罗米芬(CC),人绝经期尿促性素(HMG),人绒毛膜绒促性素(HCC)对其分别治疗3周期后,采用B超、性激素测评与宫颈黏液评判定期对患者排卵情况进行监测。结果患者治疗期的妊娠率为42.83%,停药3个月内的妊娠率为14.58%,患者总妊娠率为57.41%。结论 CC、HMG、HCC诱导排卵,妊娠率明显提高,能够有效治疗内分泌功能障碍不孕,值得临床应用与推广。
Objective To investigate the efficacy of drugs in treating infertility with follicular dysplasia caused by endocrine dysfunction and to summarize medical experience so as to provide reference for clinical application. Methods Eighty-five patients with infertility with endocrine dysfunction admitted to our hospital in 2011 were treated with clomiphene citrate (CC), human menopausal urokinase (HMG) and human chorionic villus stimulating hormone (HCC) for 3 cycles After the use of B ultrasound, sex hormone evaluation and cervical mucus evaluation of ovulation in patients with regular monitoring. Results The pregnancy rate of the patients was 42.83% during the treatment period, 14.58% within 3 months of withdrawal, and the total pregnancy rate was 57.41%. Conclusion CC, HMG and HCC induce ovulation, the pregnancy rate is significantly improved, which can effectively treat endocrine dysfunction and infertility, which is worthy of clinical application and promotion.