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为利用高压均质技术降低烟用料液中微生物的数量,以减缓其发酵作用,延长料液的贮藏时间,选取均质压力90~180 MPa,均质次数1~10次,通过Weibull模型对料液微生物致死曲线进行拟合,并预测料液杀菌效果.结果显示:①提高均质压力、升高入料温度和增加均质次数可有效提升对料液中微生物的杀伤效果,降低菌落数量;②均质压力180 MPa,入料温度40℃,均质处理5次后的料液,较正常生产的料液贮藏期可延长8~10 d;③Weibull模型能较好地拟合料液中醋酸杆菌的杀菌动力学方程(R2>0.90),并有效预测不同均质压力、入料温度、均质次数组合的杀菌效果.高压均质作为一种低温物理杀菌技术,可有效降低烟用料液中的微生物数量,减缓其发酵作用,在相同条件下可延长料液的贮藏时间.“,”High pressure homogenization technology has been used to reduce the amounts of microorganisms in tobacco casings, slowing down fermentation and prolonging the storage time of the casings. Homogenization experiments were conducted between 1-10 times at the pressure of 90-180 MPa. The microorganism lethal curve for the casing was fitted by the Weibull model, and the sterilization effect on the casing was modelled. The results showed that: 1) Raising homogenization pressure and casing temperature and increasing homogenization times effectively improved the killing effect on microorganisms and reduced the number of colonies in the casing. 2) Compared with normal production conditions, the storage time of the casing was extended to 8 to 10 days after homogenization at 180 MPa, casing temperature of 40 ℃ for 5 times. 3) The Weibull model well fitted the bactericidal kinetic equation of acetobacter aceti in the casing (R2>0.90) and predicted the sterilization effect of homogenization at different pressures and casing temperatures for different durations. As a low-temperature physical sterilization technology, high pressure homogenization could effectively reduce the amounts of microorganisms in tobacco casing, slow down the fermentation and prolong the storage time of the casing under otherwise identical conditions.