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为了观察盐酸格拉司琼的止吐疗效和毒性，对５０ 例病人采用随机自身对照的方法，比较盐酸格拉司琼和康泉在相同剂量下的疗效和毒性。结果显示盐酸格拉司琼能有效预防化疗所致的恶心、呕吐，其止吐效果与康泉相近。２ 药的止呕有效率分别为８２％ 和８４％ ，完全缓解率分别为５６％ 和６２％ ，２ 药止吐效果无显著性差异，且毒副作用小。盐酸格拉司琼是１ 个与康泉疗效基本相同而无明显毒副作用的高效止吐药。
In order to observe the antiemetic efficacy and toxicity of granisetron hydrochloride, a randomized, self-controlled study was conducted in 50 patients to compare the efficacy and toxicity of granisetron and okra at the same dose. The results show that granisetron hydrochloride can effectively prevent chemotherapy-induced nausea and vomiting, and its antiemetic effect is similar to that of Kang. The antiemetic efficacies of 2 drugs were 82% and 84% respectively, and the complete remission rates were 56% and 62% respectively. There was no significant difference between the two drugs in antiemetic effect and the small toxic and side effects. Granisetron hydrochloride is a highly effective anti-emetic with the same therapeutic effect as that of healthy milk with no significant side effects.