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子宫肌瘤是育龄期妇女最常见的实体性良性肿瘤,来源于子宫的平滑肌细胞;大多数肌瘤患者无明显症状,仅在妇科检查或手术时偶然发现。国外Baird大宗样本统计显示黑人妇女患病率达到80%,白人妇女约70%[1],其中症状性子宫肌瘤患者约为20%-40%。据国内资料统计患者多集中于30-50岁妇女,发病率达25-30%左右。临床多表现为月经改变、压迫症状、疼痛、阴道分泌物增多、不孕和贫血等症状[2-4]。以往对症状性患者多采用传统手术或药物治疗,1995年法国学者Ravina等[5]首次报道将子宫动脉栓塞(uterinearterialembolizationUAE)用于治疗子宫肌瘤,其临床疗效与手术切除治疗相仿。与传统外科手术比较,UAE具有操作简单,创伤小,并发症较少等优点,近年来在国内外均较为广泛应用,本文就其概况做一综述。
Uterine fibroids are the most common solid benign tumors in women of childbearing age, derived from the smooth muscle cells of the uterus; most fibroids patients without obvious symptoms, only occasionally found during gynecological examination or surgery. A large sample of foreign Baird statistics show that black women prevalence rate of 80%, about 70% of white women [1], of which about 20% -40% of patients with symptomatic uterine fibroids. According to statistics of domestic patients and more concentrated in 30-50 years old women, the incidence rate of 25-30%. Clinical manifestations of menstrual changes, oppression symptoms, pain, increased vaginal discharge, infertility and anemia and other symptoms [2-4]. In the past the traditional method of symptomatic patients with more surgery or drug treatment, 1995 French scholar Ravina [5] first reported the uterine artery embolization (uterinearterialembolizationUAE) for the treatment of uterine fibroids, and its clinical efficacy and surgical resection treatment is similar. Compared with traditional surgical procedures, UAE has the advantages of simple operation, less trauma and less complications. It has been widely used at home and abroad in recent years. This article reviews its general situation.