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目的了解不育不孕症患者术前病毒感染状况,并探讨检测术前4项在不孕不育患者中的临床意义。方法选取2010年1月-2012年12月医院进行侵入性治疗的不孕不育患者4 935例,术前采用ELISA法对所有患者的乙型肝炎表面抗原(HBsAg)、艾滋病抗体(抗HIVⅠ/Ⅱ型)、丙型肝炎抗体(抗HCV)以及梅毒抗体(TP-AB)进行检测,并分析患者的病毒感染情况。结果不育不孕症患者中HBsAg检测阳性率为8.67%,其中男性9.00%,女性8.33%;HCV抗体检测阳性率为0.26%,其中男性0.28%,女性0.25%;TP-AB检测阳性率为2.94%,其中男性1.78%,女性4.16%;HIV抗体的检测阳性率为0;2010-2012年患者的HBsAg、抗HCV、抗HIVⅠ/Ⅱ型及TP-AB的阳性率比较差异无统计学意义,但TP-AB的感染率呈不断上升趋势。结论对不孕不育患者进行治疗前有效检测术前4项对其预防感染、及时治疗以及减少医疗纠纷具有重要意义。
Objective To understand the preoperative virus infection in patients with infertility infertility and to explore the clinical significance of detecting 4 preoperative patients in infertility patients. Methods A total of 4 935 infertility patients who underwent invasive treatment in our hospital from January 2010 to December 2012 were enrolled in this study. Preoperatively, all patients were tested for anti-HBsAg, anti-HIV / Ⅱ), hepatitis C (anti-HCV) and syphilis antibody (TP-AB) were detected, and the patient’s viral infection was analyzed. Results The positive rate of HBsAg in infertility infertility patients was 8.67%, which was 9.00% in males and 8.33% in females. The positive rate of HCV antibodies was 0.26% in males and 0.28% in males, and 0.25% in females. The positive rate of TP-AB was 2.94%, of which 1.78% were male and 4.16% were female; the positive rate of HIV antibody was 0; there was no significant difference in the positive rates of HBsAg, anti-HCV, anti-HIVⅠ / Ⅱ and TP-AB between 2010 and 2012 , But the infection rate of TP-AB showed a rising trend. Conclusions It is of great significance to effectively detect 4 preoperative infectives in patients with infertility for prevention of infection, timely treatment and reduction of medical disputes.