皮质下动脉硬化性脑病是一种缓慢进展的老年脑血管病,其临床表现多样,加上影像学上有其特殊表现已引起临床上的重视。本文结合最新文献对其病因、发病机理、临床表现、实验室检查及影像学表现、诊断、鉴别诊断、治疗问题,分别给予综述。 Subcortical arteriosclerotic encephalopathy is a slowly progressing senile cerebrovascular disease, its clinical manifestations are diverse, with its special imaging has attracted clinical attention. This article combines the latest literature on its etiology, pathogenesis, clinical manifestations, laboratory tests and imaging findings, diagnosis, differential diagnosis, treatment issues were reviewed.