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研究糠秕孢子菌对培养角质形成细胞产生细胞因子的影响及电镜观察。结果发现糠秕孢子菌能刺激角质形成细胞分泌IL 1α的量逐渐增加。与对照组相比均有显著差异。但IL 2、IL 4、IL 10、TNF α、IFN γ等的分泌量与对照组相比 ,统计学处理无显著性差异。电镜观察显示 ,共同培养24h后 ,角质形成细胞发生变性坏死。
Effects of Pityriasis pipiens pallens on the production of cytokines by cultured keratinocytes and electron microscope observation. The results showed that Pityrosporum spores can stimulate keratinocyte secretion of IL 1α gradually increased. Compared with the control group were significantly different. However, the secretion of IL 2, IL 4, IL 10, TNF α, IFN γ and other secretions compared with the control group, no statistically significant difference. Electron microscopy showed that after cultured for 24h, keratinocytes degenerated and necrotic.