在成人和儿童脑膜炎中,常见的致病菌仍是脑膜炎球菌,流感杆菌和肺炎球菌。大肠杆菌和肺炎杆菌多见于神经外科手术病人中,糖尿病患者,免疫缺陷病人,尿路感染患者等易诱发革兰氏阳性杆菌脑膜炎。病原不明的细菌性脑膜炎约占20％,鉴于当前常规抗生素的治疗,尚不能获得满意的治疗效果。目前国外学者推荐羟羧氧酰胺菌素治疗儿童,成人革兰氏阳性菌所致的脑膜炎,是 In adult and childhood meningitis, common pathogens are still meningococci, influenza and pneumococcus. Escherichia coli and Klebsiella pneumonia are more common in neurosurgical patients, patients with diabetes, immunodeficiency patients, urinary tract infections and other susceptible gram-positive bacilli meningitis. Pathogenic bacterial meningitis is unknown about 20%, given the current treatment of conventional antibiotics, can not yet get a satisfactory therapeutic effect. At present, foreign scholars recommend hydroxycarbamide treatment of children, adult gram-positive meningitis caused by bacteria is