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本文对179名围产期正常和窒息新生儿进行了末梢血乳酸脱氢酶同功酶（LDHi）活性测定，并对其与日龄、孕周、出生体重、Apgar评分、经皮胆红素测定值、窒息程度与预后的关系进行了分析，结果表明，LDHi的改变与新生儿的缺氧程度和预后有密切关系，窒息组LDH5及LDH5／LDH1比值明显升高,LDH1-3明显下降，其改变程度与新生儿窒息程度成正比。
In this paper, peripheral blood lactate dehydrogenase isozyme (LDHi) activity was measured in 179 perinatal normal and asphyxiated neonates, and its relationship with age, gestational age, birth weight, Apgar score, transcutaneous bilirubin The results showed that the change of LDHi was closely related to the degree of hypoxia and the prognosis of newborn infants, the ratio of LDH5 and LDH5 / LDH1 in asphyxia group was significantly increased, LDH1-3 was significantly decreased, The degree of change is directly proportional to the degree of neonatal asphyxia.