目的 对脉络膜恶性黑色素瘤误诊原因进行分析。方法 对临床上可疑为恶性脉络膜黑色素瘤行眼球摘除或眶内容剜除。结果 将摘除组织行病理切片均报告为恶性脉络膜黑色素瘤。讨论 脉络膜恶性黑色素瘤，占成年人眼内恶性肿瘤的首位，临床诊断上易和许多眼底疾病相混淆，为提高诊断率，应详细询问病史，仔细检查眼底及作相应的物理检查。 Objective To analyze the misdiagnosis of choroidal melanoma. Methods Clinically suspected malignant choroidal melanoma was performed with enucleation or debulking. Results The pathological sections of the removed tissue were all reported as malignant choroidal melanoma. Discussion Choroidal melanoma, which accounts for the first malignant tumor in the eye in adults, is easily confused with many fundus diseases in clinical diagnosis. In order to improve the diagnostic rate, a detailed history should be asked, and the fundus should be carefully examined and the corresponding physical examination performed.