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方法所有患者口服阿斯匹林150毫克。静脉给予溶栓药物(链激酶、组织型纤溶酶原激活剂、Antistreplase),此后15分钟,静脉给予美托洛尔15毫克或阿替洛尔5毫克,每日二次,发病后3小时开始直至出院。溶栓后6小时开始静脉滴注2.5万单位肝素,维持24小时以上。如有指征,24小时至72小时或更早常规冠脉造影。在出院前进行70%亚极量负荷试验或在一个月随访时进行90%负荷试验。凡有左主干或三支冠脉病变和左室功能损害的患者、凡有自发性或诱发性心肌缺血的患者,进行冠脉成形术或搭桥术。
Methods All patients received aspirin 150 mg. Intravenous thrombolytic drugs (streptokinase, tissue-type plasminogen activator, Antistreplase), 15 minutes after the intravenous metoprolol 15 mg or atenolol 5 mg twice daily, 3 hours after onset Start until discharged. Six hours after thrombolysis began intravenous infusion of 25,000 units of heparin, maintaining more than 24 hours. If indicated, routine coronary angiography from 24 hours to 72 hours or earlier. A 70% sub-maximal load test was performed prior to discharge or a 90% load test at one-month follow-up. Where left main or three coronary lesions and left ventricular dysfunction in patients with spontaneous or induced myocardial ischemia in patients with coronary angioplasty or bypass surgery.