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目的:研究西宁地区妊娠高血压疾病患者血浆内皮素及心钠素的变化;方法:测定西宁地区正常妊娠孕妇、妊娠高血压疾病孕妇及非妊娠健康妇女血浆内皮素及心钠素水平并与平原地区进行对比;结果:西宁地区妊娠高血压疾病组血浆内皮素和心钠素含量显著高于正常妊娠组(P<0.01),且高于平原地区组(P<0.01);正常妊娠组又显著高于非妊娠组(P<0.01);妊娠高血压疾病组中内皮素和心钠素水平随病情严重程度的增加而升高;结论:内皮素及心钠素和高原地区妊娠高血压疾病的发生、发展有重要的关系。
Objective: To study the changes of plasma endothelin and atrial natriuretic peptide in patients with pregnancy-induced hypertension (BPH) in Xining area.Methods: The levels of plasma endothelin and atrial natriuretic peptide in normal pregnant women, pregnant women with pregnancy-induced hypertension (BPH) and non-pregnant women (P <0.01). The levels of endothelin and atrial natriuretic peptide in pregnancy-induced hypertension group were significantly higher than those in normal pregnancy group (P <0.01), and were significantly higher in normal pregnancy group (P <0.01). The levels of endothelin and atrial natriuretic peptide in pregnancy-induced hypertension group increased with the increase of the severity of the disease.Conclusion: Endothelin, atrial natriuretic peptide and hypertensive disorder of pregnancy-induced hypertension Occurrence, development has an important relationship.