目的:准确了解包头地区出生缺陷发生情况,找出适合本地具体情况的干预措施,促进本地出生人口素质的提高。方法:采用回顾性调查方法,对2001～2007年出生在包头市的86576例围产儿中出生缺陷的发生情况进行回顾性分析,找出与出生缺陷发生相关联的因素,并提出相应的干预措施。结果:2001～2007年包头市各爱婴医院共出生围产儿(孕满28周到生后7天)86576例,出生缺陷数707例,出生缺陷发生率8.16‰,出生缺陷发生病种顺位是脊柱裂、唇腭裂、先天性脑积水、多指(趾)并指(趾)畸形。结论:采取适合包头市具体情况的干预措施能有效降低出生缺陷发生率。 OBJECTIVE: To accurately understand the occurrence of birth defects in Baotou area, find out the appropriate interventions for local conditions and promote the improvement of the quality of the local birth population. Methods: A retrospective survey was conducted to analyze the incidence of birth defects in 86,576 perinatal infants born in Baotou City from 2001 to 2007. The factors associated with birth defects were identified, and the corresponding interventions were put forward . Results: A total of 86,576 cases of perinatal infants (28 gestational weeks to 7 days after birth) were born in all baby-friendly hospitals in Baotou from 2001 to 2007. The number of birth defects was 707 and the incidence of birth defects was 8.16%. The order of birth defects was Spina bifida, cleft lip and palate, congenital hydrocephalus, multiple finger (toe) and finger (toe) deformity. Conclusion: Taking appropriate interventions for Baotou City can effectively reduce the incidence of birth defects.