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目的探讨盐酸乌拉地尔与硝酸甘油治疗急性左侧心力衰竭的临床疗效。方法收集2012年11月至2014年6月我院收治的198例急性左侧心力衰竭患者资料,随机分为对照组和观察组,各99例。对照组患者给予硝酸甘油治疗,观察组患者给予盐酸乌拉地尔治疗,比较两组患者的治疗效果和不良反应。结果观察组患者总有效率为94.9%,对照组患者总有效率为89.9%,两组比较差异无统计学意义(P>0.05);观察组患者的不良反应发生率为2.0%,明显低于对照组的8.1%,差异有统计学意义(P<0.05)。结论盐酸乌拉地尔注射液治疗急性左侧心力衰竭临床效果满意,且不良反应少。
Objective To investigate the clinical efficacy of urapidil hydrochloride and nitroglycerin in the treatment of acute left heart failure. Methods A total of 198 patients with acute left heart failure who were admitted to our hospital from November 2012 to June 2014 were randomly divided into control group and observation group, with 99 cases each. Patients in the control group were treated with nitroglycerin, patients in the observation group were treated with urapidil hydrochloride, and the therapeutic effects and adverse reactions in both groups were compared. Results The total effective rate was 94.9% in the observation group and 89.9% in the control group, with no significant difference between the two groups (P> 0.05). The incidence of adverse reactions in the observation group was 2.0% The control group of 8.1%, the difference was statistically significant (P <0.05). Conclusion Urapidil hydrochloride injection in the treatment of acute left heart failure with satisfactory clinical results, and less adverse reactions.