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目的：比较三七总皂苷与右旋糖酐＿４０ 治疗脑梗死的疗效。方法：１０８ 例脑梗死病人，其中５４例（ 男性３３ 例，女性２１ 例；年龄５７ ａ±ｓ６ ａ） 采用三七总皂苷３０ ｍ Ｌ（７５０ ｍｇ） 加入０ ．９ ％ 氯化钠注射液２５０ ｍ Ｌ， 静脉滴注，ｑｄ。另５４ 例（ 男性３４ 例，女性２０ 例；年龄５６ ａ±７ ａ） 采用右旋糖酐＿４０ ，５００ ｍＬ 静脉滴注，ｑｄ ，２ 组均１５ ｄ 为一个疗程。结果：三七总皂苷组总有效率８９ ％ ，显效率５６ ％ ；右旋糖酐＿４０ 组总有效率７０ ％ ，显效率３２ ％ （ Ｐ＜ ０ ．０５） 。三七总皂苷对血脂、血液流变学均有显著改善（ Ｐ＜ ０ ．０１） ，不良反应较少。结论：三七总皂苷是治疗脑梗死的较好药物，优于右旋糖酐＿４０ 。
Objective: To compare the therapeutic effect of Panax notoginseng saponins and dextran_40 on cerebral infarction. Methods: Fifty-eight patients (33 males and 21 females; age 57 ± s6 a) were enrolled in this study. Of the 108 patients with cerebral infarction, 54 were treated with 30 m L of Panax notoginseng saponins (750 mg). 9% sodium chloride injection 250 m L, intravenous infusion, qd. The other 54 cases (34 males and 20 females; age 56 a ± 7 a) were treated with dextran 40 and 500 mL intravenous drip, qd and 2 groups for 15 days. Results: The total effective rate of Panax notoginseng group was 89%, the effective rate was 56%. The total effective rate was 70% and the effective rate was 32% in dextran 40 group (P <0.05). Panax notoginseng had significant improvement on blood lipid and hemorheology (P <0.01), with less adverse reactions. Conclusion: Panax notoginseng saponins is a better drug for the treatment of cerebral infarction, which is better than dextran-40.