目的：讨论平阳霉素注射治疗小儿淋巴管瘤的方法、疗效和机制。方法：对手术切除易影响美容和有可能造成功能障碍的淋巴管瘤应用平阳霉素注射治疗195例。结果：治愈142例（72．8％），显效32例（16.4％），有效18例（9．2％），无效3例（1．5％），总有效率98.5％。结论：平阳霉素注射治疗小儿淋巴管瘤简便易行，可作为首选治疗。 Objective: To discuss the method, efficacy and mechanism of pingyangmycin injection for treating lymphangioma in children. Methods: A total of 195 cases were treated with Pingyangmycin injection for lymphangioma, which is easy to affect the cosmetology and may cause dysfunction. Results: 142 cases (72.8%) were cured, 32 cases (16.4%) were effective, 18 cases (9.2%) were effective, 3 cases (1.5%) were ineffective, and the total effective rate was 98.5%. Conclusion: Pingyangmycin injection for the treatment of children with lymphangioma is simple and easy, as the preferred treatment.