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目的:观察杞菊地黄汤加减联合拉贝洛尔片治疗妊娠期高血压临床疗效。方法:按照随机数字表法将66例妊娠期高血压患者分为2组各33例,对照组采用拉贝洛尔片治疗;治疗组采用杞菊地黄汤加减联合拉贝洛尔片治疗。比较2组患者治疗前后血液流变学变化、血压情况及心率的变化情况,统计2组临床疗效及剖宫产、不良反应情况。结果:2组患者治疗后血液流变学和血压及心率较治疗前改善,且治疗组改善较对照组更佳,差异有统计学意义(P<0.05);总有效率治疗组90.9%,高于对照组66.7%,差异有统计学意义(P<0.05);治疗组剖宫产率9.1%,低于对照组39.4%,差异有统计学意义(P<0.05)。治疗期间未见明显不良反应。结论:应用杞菊地黄汤加减联合拉贝洛尔片治疗妊娠期高血压临床疗效良好且安全。
Objective: To observe the curative effect of Qiju Dihuang Decoction combined with labetalol in the treatment of gestational hypertension. Methods: According to the random number table method, 66 cases of gestational hypertension were divided into two groups of 33 cases. The control group was treated with labetalol tablets. The treatment group was treated with Qiju Dihuang Decoction combined with labetalol tablets. The changes of blood rheology, blood pressure and heart rate before and after treatment were compared between the two groups. The clinical curative effect and cesarean section and adverse reactions of the two groups were statistically analyzed. Results: The hemorrheology, blood pressure and heart rate of two groups were better than those before treatment, and the improvement in the treatment group was better than that in the control group (P <0.05). The total effective rate was 90.9% in the treatment group (66.7%) in the control group, the difference was statistically significant (P <0.05). The rate of cesarean section in the treatment group was 9.1%, which was lower than that in the control group (39.4%), the difference was statistically significant (P <0.05). No significant adverse reactions during treatment. Conclusion: The application of Qiju Dihuang Decoction plus labetalol tablets in the treatment of gestational hypertension clinical efficacy is good and safe.