众所周知,幼小的动物能够毫不费力地修复自我组织,这种能力在成年人类中能恢复吗?波士顿儿童医院干细胞项目最新研究表明,完全有可能。通过重新激活一般活跃于胚胎干细胞中的休眠基因Lin28a,研究人员能够再生小鼠模型的头发,修复软骨、骨、皮肤以及其他软组织。该研究还发现,Lin28a通过提高线粒体的代谢,对促进组织修复起到了一定作用——成为细胞产生能量的引擎。这表明,一个看似平凡的细胞“看家”功能,却可以打开一条通往再生治疗的 As we all know, young animals can easily repair self-organization, this ability to recover in adults? Boston Children’s Hospital stem cell project, the latest research shows that it is entirely possible. By reactivating Lin28a, a dormant gene commonly found in embryonic stem cells, researchers regenerate the hair of a mouse model to repair cartilage, bone, skin and other soft tissues. The study also found that Lin28a plays a role in promoting tissue repair by increasing mitochondrial metabolism - an engine that produces energy in cells. This shows that a seemingly ordinary cell “housekeeping ” function, but can open a way to regenerative therapy