感染是急性白血病(AL)常见的并发症和死亡的主要原因,本文就AL 感染的几个问题讨论如下。一、AL 并发感染的原因1.中性粒细胞减少,质和量的异常:我院110例AL 发生明显感染中,粒细胞<1×~9/L者占86.3%;2.免疫功能缺陷;3.细胞毒药物直接损害消化道粘膜;4.白血病细胞对皮肤、粘膜、血管壁的浸润有利于细菌入侵;5.各种穿刺、导管使用等医源性因素增加感染的机会. Infection is a major cause of complications and deaths commonly seen in acute leukemia (AL). Several issues of AL infection are discussed below. A, the causes of AL complicated infection 1. Neutropenia, quality and quantity of abnormalities: In our hospital, 110 cases of AL significant infection, granulocytes <1 × 9 / L accounted for 86.3%; 2. Immune deficiency ; 3. Cytotoxic drugs directly damage the digestive tract mucosa; 4. Leukemia cells on the skin, mucosa, blood vessel wall invasion conducive to bacterial invasion; 5. Various puncture, catheter use and other medical factors increase the chance of infection.