目的观察轻度低温对缺血性兔脑组织的影响，了解是否对缺血性脑损伤具有保护作用，以及本实验采用的自行设计的急性不全性脑缺血模型的实用性。方法夹闭双颈总动脉结扎右椎动脉头高尾低直立位，制作脑缺血模型，松开双颈总动脉，体位平置形成缺血后再灌注，观察轻度低温在缺血发生前后脑电图、脑血流图、病理组织学的变化，测定脑组织中兴奋性氨基酸的含量。结果轻度低温治疗组兔脑电图的频率及波幅恢复率明显较对照组高。脑组织匀浆中谷氨酸（Ｇｌｕ）、天门冬氨酸（Ａｓｐ）的含量，轻度低温组高于正常体温组。脑血流图中反应脑干供血情况的枕－乳导联的频率波幅下降率明显低于反应前脑情况的额－乳导联（Ｐ＜０．０１）。结论轻度低温可减轻缺血及再灌注对脑组织的损害，促进脑电图的恢复，机理之一可能是阻止细胞内兴奋性氨基酸的过量释放，结合脑血流图的改变说明本模型是一个简便实用可靠的脑缺血再灌注模型 Objective To observe the effect of mild hypothermia on ischemic rabbit brain and to find out whether it has a protective effect on ischemic brain injury and the practicability of self-designed acute incomplete cerebral ischemia model used in this experiment. Methods The bilateral common carotid artery was ligated with the tail of the right vertebral artery and the tail of the right vertebral artery was lifted upright. The model of cerebral ischemia was established. The common carotid artery was released and the position of the common carotid artery was repositioned. The mild hypothermia was observed before and after ischemia Electrocardiogram, cerebral blood flow diagram, histopathological changes, determination of brain excitatory amino acid content. Results EEG frequency and recovery rate in mild hypothermia group were significantly higher than those in control group. The contents of glutamic acid (Glu) and aspartate (Asp) in brain tissue homogenate were higher in mild hypothermia group than those in normal body temperature group. The rate of decrease in the amplitude of the frequency of the occipital-milk lead in the cerebral blood flow response to the brainstem supply was significantly lower than that of the frontal area (P <0.01). Conclusions Mild hypothermia can reduce the damage of brain tissue by ischemia and reperfusion and promote the recovery of EEG. One of the mechanisms may be to prevent the excessive release of intracellular excitatory amino acids. Combined with changes of cerebral blood flow diagram, this model is A simple, practical and reliable model of cerebral ischemia-reperfusion