Atherothrombosis is the major cause of acute coronary syndromes and cardiovascular deaths.Platelets participate in the processes of forming and extending atherosclerotic plaques.Therefore,antiplatelet therapy is a milestone in the primary and second prevention of atherothrombotic diseases.Along with the longterm use of antiplatelet agents,the safety and drug resistance has become a big concern in clinic and new drugs possessing higher effectiveness and fewer adverse effects are needed.Abundant recent data support that traditional Chinese herbs may be a good alternative and complementary choice of new antiplatelet drugs.This review highlights the progress of antiplatelet effect of active components derived from traditional Chinese herbs based on their chemical structures.