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目的:观察百令胶囊辅助治疗早期糖尿病肾病的疗效。方法:90例早期糖尿病肾病患者随机分为治疗组与对照组各45例,两组患者在良好控制血糖、血压基础上,治疗组加用百令胶囊1g,po tid,疗程12周;治疗前后监测空腹血糖(FBG)、24 h尿微量白蛋白(UMA)定量、C反应蛋白(CRP)、尿素氮(BUN)、血肌酐(SCr)、血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)。结果:治疗组治疗后CRP、24 h UMA明显下降,与对照组比较差异有统计学意义(P<0.01)。TC、TG、LDL明显下降,与对照组比较差异有统计学意义(P<0.05)。两组疗效亦有明显差异(P<0.05)。结论:百令胶囊能够明显减少24 h UMA、CRP、TC、TG和LDL,对早期糖尿病肾病有良好的辅助治疗作用。
Objective: To observe the effect of Bailing capsule in the treatment of early diabetic nephropathy. Methods: Ninety patients with early diabetic nephropathy were randomly divided into treatment group and control group, 45 cases in each group. On the basis of good control of blood glucose and blood pressure, two groups were treated with Bailing capsule (1g, po tid) for 12 weeks. Before and after treatment The levels of FBG, UMA, CRP, BUN, SCr, TC, triglyceride (TG) were measured. , High density lipoprotein (HDL), low density lipoprotein (LDL). Results: After treatment, CRP in treatment group decreased significantly at 24 h, which was significantly different from that in control group (P <0.01). TC, TG, LDL decreased significantly, compared with the control group, the difference was statistically significant (P <0.05). There was also significant difference between the two groups (P <0.05). Conclusion: Bailing Capsule can significantly reduce 24 h UMA, CRP, TC, TG and LDL, on the early diabetic nephropathy has a good adjuvant therapy.