本文实验结果表明,40uM的氟桂嗪能产生较明显的负性肌力作用,并能明显地桔抗异丙肾上腺素和哇巴因的正性肌力作用。但氟桂嗪不影响乳头状的兴奋性、不应性和快反应动作电位,对细胞外高钾条件下异丙肾上腺素诱发的慢反应动作电位和收缩力也无影响。然而,氟桂嗪能明显地抑制哇巴因增强异丙肾上腺素诱发的慢反应收缩力的作用。 The experimental results show that 40uM flunarizine can produce more obvious negative inotropic effect, and can significantly orange positive isoproterenol and ouabain positive inotropic effect. However, flunarizine did not affect the excitability of the papillary, should not be sexual and fast response to action potential, isoproterenol-induced slow response action potential and contractility under extracellular potassium conditions. However, flunarizine significantly inhibits the effect of ouabain on isoproterenol-induced slow-response contractility.