恶性黑色素瘤(简称恶黑)1974年上海市统计为每年0.41人次/10万。国外报道占全部恶性肿瘤的1～3%。近年来发病率有上升趋势,有人估算到本世纪末发病率将超过肺癌。恶黑的治疗仍以手术切除为主。但对于术后复发、转移、不能手术的晚期病例,药物治疗则是主要手段。本文仅对化疗的现状综述如 Malignant melanoma (abbreviated as black) in 1974 in Shanghai was 0.41 person/100 thousand per year. Foreign reports account for 1-3% of all malignant tumors. In recent years, there has been an upward trend in the incidence rate. It has been estimated that by the end of this century, the incidence rate will exceed that of lung cancer. The treatment of evil black is still based on surgical resection. However, for advanced cases with recurrence, metastasis, and inoperable surgery, drug therapy is the main method. This article only summarizes the current status of chemotherapy.