论文部分内容阅读
目的:观察慢性乙型肝炎(乙肝)肝内血管病变在病理发生和发展中的作用。方法:用HE、组织化学、免疫组织化学及光镜技术,对104例乙肝患者首、末2次肝活检标本进行观察。结果:肝内血管病变有血管炎症、破坏、阻塞、增生及肝窦毛细血管化表现,是乙肝的一大组织病理学特征,与其肝实质变性、坏死、肝纤维化、肝硬变及预后密切相关。结论:肝内血管病变在乙肝的病理发生和发展中可能有重要作用。故在治疗中及时有效地改善其肝脏血供障碍,是亟待研究解决的课题。
Objective: To observe the role of intrahepatic vascular lesions in pathology and development of chronic hepatitis B (hepatitis B). Methods: HE, histochemistry, immunohistochemistry and light microscopy were used to detect the first and last liver biopsy specimens from 104 patients with hepatitis B. Results: Intrahepatic vascular lesions showed vascular inflammation, destruction, obstruction, hyperplasia and hepatic sinusoidogenesis, which was a major histopathological feature of hepatitis B, which was associated with liver degeneration, necrosis, liver fibrosis, cirrhosis and prognosis Related. Conclusion: Intrahepatic vascular lesions may play an important role in the pathogenesis and development of hepatitis B. Therefore, in the treatment of timely and effective manner to improve its liver blood supply disorders, it is urgent research to solve the problem.