论文部分内容阅读
目的 通过对顽固性颞叶癫痫病人的质子波谱 (1HMRS)和磁共振成像 (MRI)研究 ,探讨这两种方法对癫痫灶定位诊断的作用。方法 2 2例无颞叶占位的癫痫病人和 3 0例健康志愿者分别进行了1HMRS采集和MRI扫描后海马结构定量研究 ,分析NAA/Cr +Cho和DHF在癫痫组的改变及对癫痫组定侧定位的敏感性和特异性。结果 1HMRS可对 16例病人进行定侧诊断 ,并发现 10例有双侧颞叶病变。MRI可准确判断 10例海马萎缩。结论 1HMRS对颞叶癫痫定侧敏感性高于海马体积测量 ,并能发现双侧病变 ;MRI海马结构定量发现海马硬化特异性较高。
Objective To investigate the role of these two methods in the diagnosis of epileptic foci by proton spectroscopy (1HMRS) and magnetic resonance imaging (MRI) in patients with intractable temporal lobe epilepsy. Methods Twenty-two patients with epilepsy without temporal lobe and 30 healthy volunteers were subjected to quantitative 1HMRS acquisition and MRI scans respectively. The changes of NAA / Cr + Cho and DHF in epilepsy group and the changes of epilepsy group Sensitivity and specificity of site-specific localization. Results 1HMRS could diagnose 16 cases of patients and found that 10 cases had bilateral temporal lobe lesions. MRI can accurately determine the 10 cases of hippocampus atrophy. Conclusion 1HMRS is more sensitive to temporal lobe epilepsy than lateral hippocampal volume measurement, and bilateral lesions can be found. MRI hippocampal structure quantitatively identified hippocampal sclerosis.