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将米非司酮配伍米索前列醇用于药物流产,传统的给药途径为口服,完全流产率为92.5%,出血时间长者占27.2%,出血量多者占20.8%,不良反应发生率为17.2%。我们改变传统给药途径,将米索前列醇改为阴道放置,其完全流产率达95.69%,出血时间长者减至17.2%,出血多者为18.2%,不良反应发生率8.6%,结论:阴道放置米索前列醇可提高完全流产率,缩短药物流产后的出血时间,且不增加不良反应。
The combination of mifepristone and misoprostol for medical abortion, the traditional route of administration for oral administration, the complete abortion rate was 92.5%, the bleeding time was 27.2%, the more bleeding accounted for 20.8%, the incidence of adverse reactions 17.2%. We changed the traditional route of administration, the misoprostol was changed to vaginal placement, the complete abortion rate was 95.69%, the bleeding time was 17.2%, the bleeding was 18.2%, the incidence of adverse reactions 8.6%, Conclusion: Vaginal misoprostol can increase the rate of complete abortion, shorten the bleeding time after medical abortion, and does not increase adverse reactions.