李×,男性,30岁,住院号68,290。因反复鼻衄,出血10年,发现贫血诊断为再障4年,心慌、气短、咳嗽、低热3个月,血红蛋白2克,白细胞1,700,血小板3.4万,网织红细胞O.4%,骨髓检查有核细胞增生低下,于1979年4月29日住院。患者从1969年开始,每年初夏出现鼻衄,清晨出现较多。1975年因劳累心慌、气短,面色苍黄,血红蛋白5克,白细胞3,500,中性53%,淋巴16%,血小板4万,骨髓检查造血功能低下,确诊为再生障碍性贫血。按再障治疗效果不著。1978年7月,劳累过度解过2～3次浓茶色尿。无服用对骨髓有损的药物史,无肝肾疾病及呕血黑便史,家族中无类似病史。查体:体温37℃,脉搏120,血压164/70。面色腊黄,呈重度贫血貌,巩膜轻度黄染,皮肤粘膜 Li ×, male, 30 years old, hospital number 68,290. Due to repeated epistaxis, bleeding for 10 years and found anemia diagnosed as aplastic anemia 4 years, palpitation, shortness of breath, cough, fever 3 months, 2 grams of hemoglobin, white blood cells 1,700, platelets 34,000, reticulocyte O.4%, bone marrow examination Melanocytic hyperplasia was low and was hospitalized on April 29, 1979. Patients from the beginning of 1969, early each year appear epistaxis, appear more in the early morning. 1975 due to fatigue palpitation, shortness of breath, pale yellow, hemoglobin 5 grams, 5300 leukocytes, 53% neutral, lymphatic 16%, platelets 40,000, bone marrow hematopoietic dysfunction, diagnosed with aplastic anemia. According to aplastic anemia treatment does not work. July 1978, overworked over 2 to 3 times dark brown urine. No medication for bone marrow damage, no history of liver and kidney disease and hematemesis mellitus, no similar family history. Physical examination: body temperature 37 ℃, pulse 120, blood pressure 164/70. Pale yellow, showed severe anemia, scleral mild yellow dye, skin and mucous membranes