1脂联素的生理脂联素是至今为止发现的唯一一种当脂肪组织容积变大时其血浆浓度反而下降的脂肪细胞因子[1]。研究发现,脂联素水平降低预示着高胰岛素血症和高血糖症的发生,任何影响脂联素水平的因素包括脂联素基因突变,基因转录水平的异常调节等都可以导致脂联素水平降低,从而 1 Adiponectin Physiological adiponectin is the only adipocytokine that has been found so far to decrease in plasma concentration as the volume of adipose tissue increases [1]. The study found that decreased adiponectin predicts hyperinsulinemia and hyperglycemia, any factors that affect the level of adiponectin, including adiponectin gene mutations, abnormal regulation of gene transcription levels can lead to adiponectin levels Lower, thus