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目的检测反复呼吸道感染患儿血硒水平及进行补硒治疗,探讨硒缺乏与儿童发生RR I之间的关系,为临床治疗提供依据。方法病例组选取4岁龄RR I患儿60例,随机分为常规治疗组与补硒组。常规治疗组与补硒组均给予抗感染及对症治疗,补硒组另进行补硒治疗。病例组随访6个月,复查血清硒水平,观察并记录呼吸道感染的复发次数,进行t检验。对照组健康4岁儿童30例,检测其血清硒水平与病例组进行比较,进行方差分析。结果病例组血清硒水平低于对照组,两组比较其差异有统计学意义(P<0.05);采用不同的方法治疗后两病例组的呼吸道感染复发次数比较有显著差异(P<0.05)。结论RR I患儿血清中硒水平低于正常健康儿童;硒缺乏与儿童RR I有关。
Objective To detect selenium levels in children with recurrent respiratory tract infections and to study the relationship between selenium deficiency and RR I in children and to provide basis for clinical treatment. Methods Sixty cases of 4-year-old RR I children were selected and randomly divided into routine treatment group and selenium-supplemented group. Conventional treatment group and selenium group were given anti-infective and symptomatic treatment, selenium group selenium treatment. The case group was followed up for 6 months. The serum selenium level was reviewed. The number of recurrent respiratory infections was observed and recorded. The t test was performed. The control group of 30 healthy 4-year-old children, serum selenium levels were compared with the case group for analysis of variance. Results The level of serum selenium in the case group was lower than that in the control group. There was significant difference between the two groups (P <0.05). There were significant differences in the number of recurrent respiratory infections between the two groups after treatment by different methods (P <0.05). Conclusions Selenium levels in children with RR I are lower than those in normal children; selenium deficiency is associated with RR I in children.