目的 :分析乳腺癌皮肤受累概率 ,探讨乳腺癌皮肤切除范围。方法 :对 4 0例乳腺癌肿瘤表面皮肤做连续切片病理检查 ,了解皮肤受累情况。结果 :4 0例乳腺癌中 ,除 1例Paget病患者皮肤受累外 ,其余均未见受累 ,皮肤受累率 2 .5 %。结论 :如无皮肤受累的临床迹象 ,乳腺癌手术时皮肤切除范围不必过大 ,早期乳腺癌可以考虑保留皮肤的皮下乳腺切除术 Objective: To analyze the probability of skin involvement in breast cancer and explore the scope of skin resection for breast cancer. Methods : A series of pathological examinations were performed on 40 cases of breast cancer tumor surface skin to understand the skin involvement. Results : Of the 40 cases of breast cancer, except 1 case of skin involvement in Paget’s disease, the rest were not affected. The skin involvement rate was 2.5 %. Conclusion : If there is no clinical evidence of skin involvement, the scope of skin resection should not be too large during breast surgery. Early breast cancer can be considered to retain subcutaneous breast resection of the skin.