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目的:了解海口市HBsAg阳性孕产妇乙型肝炎母婴传播阻断干预措施的实施状况,为防治乙型肝炎流行提供依据。方法:采用回顾性研究方法,对HBsAg阳性孕产妇进行问卷调查。结果:84.65%的孕妇在孕期注射了HBIG,75.35%孕妇的孩子出生后接受了主被动联合免疫;剖宫产率77.67%,30.54%剖宫产指征为携带乙型肝炎病毒;84.76%孕产妇因携带乙型肝炎病毒而行人工喂养;宫内感染率为7.35%,合并HBeAg阳性孕产妇宫内感染率20.00%,儿童慢性HBV感染率为2.94%。结论:母婴联合主被动免疫是被接受的主要乙型肝炎母婴传播阻断措施,需加强母亲为HBsAg阳性的婴儿出生后联合免疫,并重视合并HBeAg阳性孕产妇及其婴儿管理。
Objective: To understand the implementation status of HBeAg-positive mother-to-child transmission interruption intervention in HBsAg-positive pregnant women in Haikou and provide basis for prevention and treatment of hepatitis B epidemic. Methods: A retrospective study was conducted to investigate HBsAg positive pregnant women. Results: 84.65% pregnant women were injected with HBIG during pregnancy. 75.35% of pregnant women received primary and passive immunization after birth. The rates of cesarean section were 77.67%, 30.54%, those of cesarean section were HBV carriers, 84.76% The mothers were given artificial feeding because of carrying the hepatitis B virus. The intrauterine infection rate was 7.35%. The intrauterine infection rate of HBeAg positive pregnant women was 20.00%. The rate of chronic HBV infection was 2.94% in children. CONCLUSIONS: Maternal-infant combined primary and passive immunization is a major block of maternal-to-infant transmission of hepatitis B that is undergoing maternal and infant immunization. The combined immunization of mothers with HBsAg-positive babies needs to be strengthened, and the management of HBeAg-positive pregnant women and their infants should be emphasized.