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目的分析病毒性脑炎患者预后相关的危险因素。方法回顾性分析67例病毒性脑炎患者的临床资料,通过单因素分析及多因素Logistic回归分析寻找与预后相关的危险因素。结果单因素分析结果显示,不同预后患者性别、年龄、外周血白细胞、发热、脑CT异常及上感病史比较差异无统计学意义(P均>0.05);而脑MRI异常、脑电图异常、意识障碍、癫痫、精神行为异常及肌力异常比较差异有统计学意义(P均<0.01)。多因素Logistic回归分析结果显示,意识障碍(OR=1.418,95%CI(0.724,2.196),P<0.05)和脑MRI异常(OR=16.264,95%CI(10.869,28.114),P<0.01)是影响病毒性脑炎患者预后的独立危险因素。结论病毒性脑炎患者若出现意识障碍或脑MRI异常者预后较差,应及时治疗。
Objective To analyze the risk factors associated with the prognosis of patients with viral encephalitis. Methods The clinical data of 67 patients with viral encephalitis were retrospectively analyzed. Univariate analysis and multivariate Logistic regression analysis were used to find the risk factors associated with prognosis. Results The results of univariate analysis showed that there was no significant difference in the gender, age, peripheral blood leucocyte, fever, brain CT abnormalities and the history of sensation between different prognosis patients (all P> 0.05) There were significant differences in consciousness disorder, epilepsy, mental disorders and muscle abnormalities (all P <0.01). Multivariate Logistic regression analysis showed that disturbance of consciousness (OR = 1.418, 95% CI 0.724, 2.196, P <0.05) and abnormal brain MRI (OR 16.264, 95% CI 10.869, 28.114, P <0.01) Is an independent risk factor affecting the prognosis of patients with viral encephalitis. Conclusion If patients with viral encephalitis have impaired consciousness or brain MRI abnormalities, their prognosis is poor, they should be treated promptly.